منابع مشابه
Steroid Assays in Paediatric Endocrinology
Most steroid disorders of the adrenal cortex come to clinical attention in childhood and in order to investigate these problems, there are many challenges to the laboratory which need to be appreciated to a certain extent by clinicians. The analysis of sex steroids in biological fluids from neonates, over adrenarche and puberty present challenges of specificities and concentrations often in sma...
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Paediatric endocrinology is a highly specialised area of clinical medicine with many experts with specific knowledge distributed over a wide geographical area. The European Society for Paediatric Endocrinology (ESPE) is an example of such a body of experts that require regular collaboration and sharing of data and knowledge. This paper describes work, developed as a corollary to the VOTES proje...
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A surgically removed pituitary adenomas, approximately 30-35% appear to be silent, unassociated with clinical or biochemical evidence of any anterior pituitary hormone excess (1, 2). However, with routine immunocytochemical staining of the pituitary tumor tissue, immunoreactive hormone material can be demonstrated in a substantial number of these seemingly nonfunctioning tumors (2). Clinically ...
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in such a way as to test the hypothesis; the observations gained from the experiment are incorporated in a new hypothesis. Bernard recognized that the success or failure of the procedure was in great part dependent upon the attitude of the investigator and demanded open-mindedness, doubt, and unprejudiced observation. Today we recognize that investigation of the properties of living material ca...
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many as a single entity. The aetiology of the disease remains obscure. It has, however, been clearly established that thyroid-stimulating hormone (TSH) is not responsible for the excessive thyroid activity. An abnormal thyroid stimulator (known as long-acting thyroid stimulator, or LATS), which is both chemically and immunologically distinct from TSH, is found in the serum of many patients with...
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ژورنال
عنوان ژورنال: Archives of Disease in Childhood
سال: 1996
ISSN: 0003-9888,1468-2044
DOI: 10.1136/adc.74.3.275-a